Product Information

May kill or suppress many (more than 900) types of Detrimental Micro-organisms including Detrimental Fungi, Moulds and Yeasts including Candida albicans. It is regarded by some as the treatment of choice against Candida albicans proliferation. Grapefruit Seed extract may inhibit some types of Viruses and is presently under investigation as a potential inhibitor of the HIV virus that causes (AIDS). It is also being investigated as a means of treating the various opportunistic (secondry) infections (from Detrimental Bacteria, Fungi, Parasites and Viruses) that occur in conjunction with AIDS. Grapefriut Seed extract may accelerate the recovery from the Common Cold and may minimize the symptoms of the Common Cold & Influenza and may be a useful treatment for Measles and Rheumatoid Arthritis (where Rheumatoid Arthritis is caused by any of the Detrimental Bacteria).

Description

Grape Seeds are the Seeds from seeded species of the Grape.

Botanical Name - Vitis vinifera

Grapes are from the Vitaceae family.

Health Benefits of Grape Seeds

Other health benefits of Grape Seeds are described in the topic for Oligomeric Proanthocyanidins.

Aging Process

Grape Seeds (extract) may retard the progression of the Aging Process (due to the powerful Antioxidant properties of the Oligomeric Proanthocyanidins (OPCs) content of Grape Seeds).
Grape Seeds (extract) may possess Life Extension potential (due to the powerful Antioxidant properties of the Oligomeric Proanthocyanidins (OPCs) content of Grape Seeds).

Cardiovascular System

Grape Seeds (extract) may help to prevent Atherosclerosis (due to the OPC content of Grape Seeds).
Grape Seeds (100 mg of Grape Seed extract per day) may increase the strength of the Capillaries.
Grape Seeds (extract) may help to lower Blood Pressure in Hypertension patients (due to the OPC content of Grape Seeds inhibiting Angiotensin Converting Enzyme (ACE)).
Grape Seeds (extract) may help to prevent Ischemic Heart Disease (due to the OPC content of Grape Seeds).
Grape Seeds (extract) may help to prevent Heart Attack.
Grape Seeds (extract) may alleviate Varicose Veins (by inhibiting the destruction of Collagen in the walls of Veins):

• Grape Seeds (extract) may alleviate Hemorrhoids (by inhibiting the destruction of Collagen in the walls of the Veins that supply the Anus).

Grape Seeds (extract) may help to prevent (ischemic) Stroke by inhibiting the abnormal Blood Clotting that leads to (ischemic) Stroke.
Grape Seeds (100 - 300 mg of Grape Seed Extract per day) may alleviate Venous Insufficiency.

Cells

Grape Seeds (extract) may help to prevent damage to the Deoxyribonucleic Acid (DNA) content of Cells.
Grape Seeds (extract) may exert Antioxidant effects that protect the Membranes of the Mitochondria from the toxic effects of Free Radicals generated during Energy production in the Mitochondria.

Digestive System

Grape Seeds (extract) may reduce the severity of Pancreatitis (due to the Antioxidant properties of the OPCs content of Grape Seeds).

Eyes/Vision

Grape Seeds (extract) may help to prevent Bloodshot Eyes (by increasing the strength of the Capillaries, thereby preventing their unwarranted leakage as occurs in Bloodshot Eyes).
Grape Seeds may help to prevent Cataracts.
Grape Seeds may protect the Cornea from degradation by Proteolytic Enzymes such as Collagenase.
Grape Seeds may alleviate Eye Fatigue.
Grape Seeds (extract) may alleviate Night Blindness.
The OPCs content of Grape Seeds concentrate in the Retina of the Eyes and may thereby enhance the health of the Eyes.

Grape Seeds (extract) may be a useful treatment for (diabetic) Retinopathy (OPCs from Grape Seeds strengthen the Capillaries that supply the Retina).
Grape Seeds (extract) may help to prevent Short-Sightedness (by improving the structural integrity of the Capillaries that supply the Retina).
Grape Seeds (extract) may improve various aspects of Sight including the ability to adapt to glare and dark lighting.

Hair

Grape Seeds (extract) may stimulate Hair growth in persons with Hair Loss (due to the Catechin, Epicatechin and OPCs content of Grape Seeds):

• Studies on mice have demonstrated that the constituents of Grape Seeds may stimulate the proliferation of Hair Follicles and may convert the Hair growth cycle from the telogen phase to the anagen phase. - The ability of Grape Seeds to stimulate Hair growth may be due (in part) to the ability of some of the OPCs in Grape Seeds inhibiting Protein Kinase C.
  

Grape Seeds (extract) may help to prevent the mutations that initiate some forms of Cancer and may help to kill some types of Cancer cells including:

• Breast Cancer
• Colon Cancer
• Leukemia
• Lung Cancer
• Mouth Cancer
• Prostate Cancer
• Skin Cancer
• Stomach Cancer

Grape Seeds contain various Antioxidant chemicals (primarily Polyphenols including OPCs):

• Grape Seeds (extract of) deactivate Hydroxyl Free Radicals (primarily due to their OPCs content).

Grape Seeds (extract of) quench Superoxide Free Radicals. Grape Seeds (extract) may inhibit the oxidation of LDL Cholesterol. Grape Seeds (extract) may inhibit the damage to Liver Cells (hepatocytes) that occurs as a result of Paracetamol overdose.
Grape Seeds (extract) may facilitate weight loss in persons afflicted with Obesity (due to the ability of Grape Seeds to inhibit the activity of Pancreatic Lipase and Lipoprotein Lipase).

Nervous System

Grape Seeds (extract) may alleviate Restless Legs Syndrome.

Orthodox Medical Procedures

Grape Seeds (extract) (150 - 300 mg per day) may reduce the Edema and Inflammation that occurs following Surgery (due to the Oligomeric Proanthocyanidins (OPCs) content of Grape Seeds).

Sexual System

Grape Seeds (extract) may reduce the severity of the symptoms of Endometriosis.

Skin

Grape Seeds (extract applied topically or consumed orally) may inhibit the development of Wrinkles (by enhancing the body's renewal of Collagen, inhibiting excessive Cross-Linking and inhibiting the Hyaluronidase enzyme).

Water/Water Balance
Grape Seeds (extract) may alleviate Edema (by improving the structural integrity of Blood Vessels). 

Grape Seeds may Enhance the Function of these Substances

Carbohydrates

Grape Seeds (extract) may protect the body’s Hyaluronic Acid content from destruction by the Hyaluronidase enzyme (due to the OPCs content of Grape Seeds inhibiting the activity of Hyaluronidase).

Immune System Chemicals

Grape Seeds (extract) may stimulate the production of Interferon Gamma.

Nucleic Compounds

Grape Seeds (extract) may help to prevent damage to the Deoxyribonuceic Acid (DNA) content of Cells (due to the OPCs content of Grape Seeds).

Proteins

Grape Seeds (extract) may protect the body’s Collagen content from destruction by the Collagenase enzyme (due to the OPCs content of Grape Seeds inhibiting the activity of Collagenase).
Grape Seeds (extract) may protect the body’s Elastin content from destruction by the Elastase enzyme (due to the OPCs content of Grape Seeds inhibiting the activity of Elastase).

Grape Seeds may Inhibit these Potentially Toxic Substances

Enzymes

Grape Seeds (extract) may inhibit the activity of Collagenase (the enzyme that degrades the body’s Content).
Grape Seeds (extract) may inhibit the activity of Elastase (the enzyme that degrades the body’s Elastin).
Grape Seeds (extract) may inhibit Histidine Decarboxylase (due to the Oligomeric Proanthocyanidins (OPCs) content of Grape Seeds).
Grape Seeds (extract) may inhibit the activity of Hyaluronidase (the enzyme that degrades the body’s Hyaluronic Acid).
Grape Seeds (extract) may inhibit Ornithine Decarboxylase.
Grape Seeds may inhibit Protein Kinase C (due to the ability of some types of Oligomeric Proanthocyanidins (OPCs) in Grape Seeds to inhibit Protein Kinase C).

Pharmaceutical Drugs

Grape Seeds (extract) may protect healthy Cells from the toxic effects of the excessive generation of Free Radicals that occurs as a result of the Anti-Cancer Pharmaceutical Drugs in Chemotherapy to treat Cancer.
Grape Seeds (extract) may inhibit the damage to Liver Cells (hepatocytes) that occurs as a result of Paracetamol overdose.

Grape Seeds Contain these Substances

(mg of substance per 100 grams)

Fatty Acids
20,000
Monounsaturated
Oleic Acid
3,400
Polyunsaturated Linoleic Acid 14,200
Saturated Stearic Acid 2,400
Phenolic Acids Ellagic Acid
Polyphenois Oligomeric
Proanthocyanidins
(OPC): Procyanidin B1
Procyanidin B2
Procyanidin B3
Procyanidin B4
Procyanidin B5
Procyanidin C1
Procyanidin B2-3'-O-gallate
Many Others
Catechins: Catechin
Epicatechin
Other Resveratrol

Dosage Recommendations

General Therapeutic Dosage

The general therapeutic dosage of Grape Seed extract for therapeutic purposes is 100 - 400 mg per day. This dosage level provides 95 - 380 mg of the primary active ingredient, Oligomeric Proanthocyanidins (OPC) if a 95% standardized Grape Seed Extract product is used.

Skin

The usual dosage of Grape Seed extract for the prevention and possible reversal of some aspects of Skin Aging is 200 mg per day.

Safety

Grape Seeds are regarded as a safe therapeutic agent. No side effects have been observed.

Grape Seeds vs. Pycnogenol

Formulas

Grape Seed extract is an ingredient in several specific purpose products designed to improve Cardiovascular function (e.g. 20 mg Grape Seed Extract combined with Bilberry and Ginkgo biloba).
Grape Seed extract is an ingredient in some mixed Bioflavonoids products (tablets).

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