Product Information

The latest anti-aging supplement - Carnosine is a potent anti-oxidant that prevents cell damage and improves cell function

This description concerns oral carnosine (as L-Carnosine) and carnosine eye-drops (as N-acetylcarnosine).

Carnosine (not to be confused with Carnitine) is a natural amino-acid that has been known about for decades. But it is only through recent Australian and British clinical and laboratory studies that the benefits of carnosine have become better known.

Carnosine has a number of interesting actions, it is a potent anti-oxidant, it helps to chelate ionic metals (i.e. flush toxins from the body), it has immune boosting properties (aid's wound healing) and is also known to reduce and prevent cell damage caused by beta amyloid (the substance found in the brain of Alzheimer disease patients). Carnosine helps protect neural tissues by blocking and inactivating beta amyloid and therefore it could help protect tissues against dementia. Recent evidence even suggests that carnosine has a important role in the sense of smell.

From the anti-aging standpoint, there are some very interesting carnosine actions, they are:

• Carnosine's ability to help prevent glycosylation- the cross linking of proteins (and DNA molecules) caused by sugar aldehydes reacting with the aminoacids on the protein molecule and creating Advance Glycosylation End-products (AGE's). If you want to see protein cross linking in action cut an apple in half and watch it turn yellow! Such anti-glycosylation may be beneficial for diabetes, cataracts, neuropathy, kidney failure and skin conditions, as well as "general" anti-aging properties, especially improving skin condition.
• In 1999, Australian researchers confirmed that carnosine increases the longevity of human fibroblast cells in the laboratory. Carnosine extended the Hayflick limit (the maximum number of times a cell can divide), from a "normal" 50 by up to an additional 10 times! Although not enough time has passed to test these results, carnosine may be a supplement of choice for longevity. It has been shown that animals with higher levels of carnosine appear to live longer than their controls.
• The Russians use Carnosine (in an eye-drop form) to help eradicate senile cataract problems with great success, (their clinical trials indicate an eye-condition improvement of 41.5% to 100% for patients within a 6-month period with sustainable results 24-months later). This type of carnosine eye-drop may have very important anti-aging eye functions because it is breaking protein cross-links, NOT just inhibiting them. Note however, that the Russians have been using a "special" kind of carnosine known as N-alpha acetylcarnosine or NAC for this purpose. It is not "just" L-carnosine as an eye-drop. Dr. Mark Babizhayev, one of the scientists behind the Russian clinical trials stated; "L-carnosine means nothing for the treatment of human cataracts because it readily becomes hydrolyzed with the serum carnosinase in the aqueous humor.Besides, L-carnosine appears even dangerous for the treatment of ocular disorders, as it gradually releases histamine via the activity of histidine decarboxylase."

ORAL L-CARNOSINE
Extending the Hayflick limit

Carnosine oral supplementation is a relatively new area, normal current anti-aging dosages are 50mg-150mg of L-carnosine per day, (maximum 200mg day) with occasional breaks. Such dosages have failed to produce any report of serious side effects or contraindications to date.

We don't recommend larger oral dosages than 200mg per day because it may be that some of the advantages of oral carnosine supplementation comes from its breakdown. Furthermore, we know of cases of disturbing muscle twitching with 1g plus dosages. You can click here to see the results of a clinical trial that show 100mg-200mg of carnosine daily are effective, and that in-fact dosages of more than 500mg daily may be less effective.

The synergetic and protective use of Lucidril (Centrophenoxine) may be beneficial with long-term oral Carnosine use.

Manufacturer's Insert

CARNOSINE ORAL / L-CARNOSINE

An anti-aging dipeptide

Pack Size: 50 x 100mg capsules

Description: L-Carnosine is one of the latest discoveries in the aminoacid field. It is a natural anti-oxidant and a potent late-stage anti-glycosylation inhibitor. Its role in helping aging, cataract, diabetes, kidney, skin problems and neuropathy is now coming to light.

Directions: Take 1 capsule, two or three times a day.

Supplement facts:

Serving Size: 1 capsules

Other ingredients: Rice flour in a gelatine capsule.

Disclaimer: This product and its statements have not been evaluated by the FDA. This product is not intended to treat, cure or prevent any disease.

Note: Keep out of reach of children. Not for use by pregnant or lactating women.