GLUCOCIN™

Glucocin™ is a natural botanical formula used traditionally for blood sugar balancing and diabetic conditions.

Ingredients: Gymnema Sylvestre, Momordica Charantia, Pterocarpus Marsupium, Trigonella Foenum-

Graecum, shilajit, and other natural botanical ingredients.

Indications: Supports healthy blood sugar balance.

Packaging/Size: 90 Tablets

The leaves of Gymnema sylvestre have hypoglycemic activity which has been reported both in animals and humans. Also, leaves of Gymnema syvestris given to diabetics have been shown to reduce urine sugar levels. The hypoglycemic extract of Gymnema sylvestris brings about blood glucose homeostasis, which in turn prevents increased glycosylation of proteins thus reversing the onset of changes leading to micro and macroangiopathy. Control of blood sugar imbalances and the associated complications are mediated through the revival or regeneration of the insulin, producing beta -cells in the islets of langerhans.

Momordica charantia fruit is traditionally used as a vegetable dish and for blood sugar conditions and is known to have hypoglycemic effect in human and experimental diabetes. Blood glucose concentrations were significantly reduced in M charantia treated diabetic animals when compared with untreated diabetic conditions (p< 0.05), but were still significantly greater (p< 0.05) than those of age-matched controls. Pterocarpus Marsupium has been proved to be effective in blood sugar imbalanced conditions by releasing insulin, by regenerating beta cells of islets of langerhans of the pancreas.

Trigonella Foenum-Graecum seeds have been shown to possess hypoglycemic properties in both animal and human subjects. The soluble dietary fiber (SDF) when fed simultaneously with glucose showed significant hypoglycemic effect in animals.

CONTRAINDICATIONS: Not to be taken with other conventional hypoglycemic products without medical supervision.

References:

• Wahl, S P and Chunekar, K C (1969) Pharmacological studies of Gymnema sylvestris R.Br. J. Sci. Res. Banaras Hindu University, Varanasi, 15: 205.
• Nadkarni, A K and Nadkarni, K M (1954) The Indian Materia Medica , Anti-diabetes. Popular book depot . Bombay. 11: pp. 15, 23, 239, 536.
• Pannerarselaun, C and Shanmugasundaram, K R (1978) Sirukurizavumiratha Charkarailuvurum (Tamil) J. Madras Univ. (Section B ) 4 : 171.
• Gharpurey, K G (1926) Gymnema sylvestris in the treatment of diabetes. Ind. Med. Gaz. 61: 155 (Abtr.)
• Shanmughasundarum, E R B et.al (1988) effect of an isolate from Gymnena sylvestre R. Br. In the control of diabetes mellitus and the associated pathological changes. Ancient science of life vol. VIII (no. 3-4): 183.
• Cunnick J. Bitter melon: research review. J Nat Med 4(1):16-21, 1993.
• Lee-Huang S et al. MAP 30, an anti-HIV protein, inhibits both ribosomal RNA function and DNA topological interconversions. 9th Intl Conf AIDS, Berlin, abstract B26-1993, 1993.
• Lee-Huang S et al. The anti-HIV activity of recombinant MAP 30 from bitter melon. 10th Intl Conf AIDS, Yokohama, abstract 114A, 1994.
• Chakravarty, B K et.al (1980) A study on hypoglycemic effect of Pterocarpus marsupium Roxb,. Indian J. of Pharmacol vol. 12 (2).
• Krishnaveni KS, Srinivasa Rao JV. An isoflavone from Pterocarpus santalinus. Phytochemistry2000;53(5):605-606. Krishnamurthi A (Ed.). Pterocarpus santalinus In: The wealth of India, Raw Materials, Vol. VIII, Council of Scientific and Industrial Research, New Delhi, 1st ed., 1969.
• Bordia A, Verma SK, Srivastava KC. Effect of ginger (Zingiber officinale Rosc.) and fenugreek (Trigonella foenumgraecum L.) on blood lipids, blood sugar and platelet aggregation in patients with coronary artery disease. Prostaglandins, Leukotrienes and Essential Fatty Acids. 1997;56(5):379-384.
• Devi BA, Kamalakkannan N, Prince PS. Supplementation of fenugreek leaves to diabetic rats. Effect on carbohydrate metabolic enzymes in diabetic liver and kidney. Phytotherapy Research. 2003;17(10):1231-1233.
• Diabet Med 1997;14:S7-S85.
• Bhattacharya, S.K. Activity of shilajit on alloxan-induced hyperglycemia in rats. Fitoterapia, Volume LXVI, No 4, 1995, pg. 328