Product Information

With Vitamins B6, B12 & Folic Acid. Homocysteine accelerates aging, has toxic effects on the Cardiovascular System, Brain & other body parts. It is recommended to use TMG in conjunction with this product.

Homocysteine is a toxic endogenous amino acid and has devastating effects on the cardiovascular system, brain and accelerates aging. Homocysteine is an unavoidable byproduct of Methionine metabolism. Standard reference ranges often differ dangerously from optimal levels. Persons seeking optimal Cardiovascular health should strive to reach Plasma Homocysteine levels of: Under 6-7 micromoles per litre. Homocysteine is a toxic amino acid found in the bloodstream. An elevated homocysteine level is more dangerous than high cholesterol. Homocysteine accelerates aging and can cause cancer. An elevated homocysteine level is more dangerous than high cholesterol and increases your chance of having a heart-attack by 40-50% (Boushey CJ, et al.; A quantitative assessment of plasma homocysteine as a risk factor for vascular disease, a meta-analysis. JAMA 1995;274:104957). Homocysteine accelerates aging and can cause cancer because it damages DNA genetic structures and impairs our cells ability to repair themselves. (Journal of Medical Hypothesis; 1998, 51[3]: p179-221)
Homocysteine increases the risk of blood clotting, causes hardening of the arteries, elevates cholesterol deposits in the heart, increases risk of chronic fatigue syndrome, Rheumatoid arthritis and Alzheimers disease. Elevated Homocysteine can aggravate Parkinson’s Disease, Memory Impairment, Age-Related Hearing Loss, Major Depression, Liver damage, Fibromyalgia and Osteoporosis.

What causes raised homocysteine?

Aging process: 30% of elderly persons (both male and female) have elevated homocysteine.
29% of vegetarians have elevated Homocysteine levels.
Alcohol, Tobacco and Coffee consumption lead to elevated Homocysteine levels.
Diabetes Mellitus Type 2 patients generally exhibit elevated Homocysteine levels.
Excessive Stress & Hypothyroidism causes elevated Homocysteine levels.
Elevated homocysteine often goes hand-in-hand with high cholesterol levels.

How can raised homocysteine be treated?

A simple blood test will determine if levels of homocysteine are elevated.

Elevated homocysteine can be treated by a combination of nutrients, at doses found in Solal’s homocysteine lowering formula: (Clarke R; Lowering blood homocysteine with folic acid based supplements: meta-analysis of randomised trials; British Medical Journal 1998, March 21)

Folic acid 2000mcg - the amount required to reduce homocysteine by 30% and is essential for the conversion of homocysteine into methionine and SAMe
Vitamin B12 (methylcobalamin form) 1000mcg – unlike the cyanocobalamin form of Vit B12, the methyl-cobalamin form is essential for the re-methylation of homocysteine into methionine and SAMe. Methylcobalamin will not produce cyaninde (a poison) in the process –unlike cyano-cobalamin.
Vitamin B6 (pyridoxine) 100mg – essential for converting homocysteine into cysteine, via the tran-sulferation pathway.
Choline bitartrate 250mg – choline is a methyl-donor. It forms betaine (TMG) which then re-methylates homocysteine into methionine and SAMe, via the re-methylation pathway.
Zinc 20mg (from 143mg zinc gluconate) – essential co-factor for the enzymatic processes involved in the detoxification of homocysteine back into methionine, SAMe and cysteine.
If required, for additional homocysteine lowering effects take Solal’s TMG capsules with the homocysteine lowering formula. TMG is approved by the Food and Drug Administration as an expensive homocysteine-lowering drug, but TMG is also sold as a low-cost dietary supplement.

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